Jirka (feminine: Jirková) is a Czech surname. It is a pet form of the given name Jiří. Notable people with the surname include:
David Jirka (born 1982), Czech rower Erik Jirka (born 1997), Slovak footballer Frank J. Jirka Jr. (1922–2000), American physician Jan Jirka (born 1993), Czech sprinter
See also A character in The Devil and Kate by Antonín Dvořák