L'Hommedieu may refer to:
L'Hommedieu (surname) Ezra L'Hommedieu (1734–1811), American lawyer and politician Stephen S. L'Hommedieu (1806–1875), American newspaper publisher and railroad executive Wallace L'Hommedieu (1833–1916), American politician Irving L'Hommedieu (1865–1931), American lawyer and politician
L'Hommedieu (middle name) Stephen L'Hommedieu Slocum (1859–1933), American military attaché Tillinghast L'Hommedieu Huston (1867–1938), American civil engineer and baseball team owner Colden L'Hommedieu Ruggles (1869–1933), American general