Kasule is a given name and a surname. It may refer to:
Given name Kasule Owen (born 1989), Ugandan footballer
Surname Abubakar Kasule, Ugandan footballer Justine Lumumba Kasule, Ugandan educator and politician Kizito Maria Kasule (born 1967), Ugandan artist and entrepreneur Noah Babadi Kasule (born 1985), Ugandan footballer Peninnah Kasule, Ugandan lawyer and corporate executive Remmy Kasule (born 1949), Ugandan lawyer and judge Vic Kasule (born 1965), Scottish footballer of Ugandan descent