In Greek mythology, Antissa () was a princess of Lesbos as the daughter of King Macar and probable sister to Methymna,Diodorus Siculus, 5.81.6 Mytilene,Stephanus of Byzantium, s.v. Mytilēnē (Μυτιλήνη) Agamede,Stephanus of Byzantium, s.v. Agamede (Ἀγαμήδη) ArisbeStephanus of Byzantium, s.v. Arisbe (Ἀρίσβη) and Issa.Stephanus of Byzantium, s.v. Issa (Ἴσσα) Her possible brothers were Cydrolaus, Neandrus, LeucippusDiodorus Siculus, 5.81.8 and Eresus.Stephanus of Byzantium, s.v. Eresos (Ἔρεσος) She was the eponym of the city Antissa on the said island.Philo, Brill's New Jacoby 790 F 26 = Stephanus of Byzantium, s.v. Antissa (Ἄντισσα) In some account, Antissa was claimed to be Macareus' wife instead.Σ vet. Homer, Iliad 24.544c.

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Diodorus Siculus, The Library of History translated by Charles Henry Oldfather. Twelve volumes. Loeb Classical Library. Cambridge, Massachusetts: Harvard University Press; London: William Heinemann, Ltd. 1989. Vol. 3. Books 4.59–8. Online version at Bill Thayer's Web Site Diodorus Siculus, Bibliotheca Historica. Vol 1-2. Immanel Bekker. Ludwig Dindorf. Friedrich Vogel. in aedibus B. G. Teubneri. Leipzig. 1888–1890. Greek text available at the Perseus Digital Library. Stephanus of Byzantium, Stephani Byzantii Ethnicorum quae supersunt, edited by August Meineike (1790–1870), published 1849. A few entries from this important ancient handbook of place names have been translated by Brady Kiesling. Online version at the Topos Text Project.