Setsuko (written: or in hiragana) is a feminine Japanese given name. Notable people with the name include:

, later of Japan , actress , Japanese volleyball player , Japanese actress and model Setsuko Klossowska de Rola (born 1942), Japanese painter Setsuko Kobori Japanese table tennis player Koizumi Setsuko (小泉節子, 1868–1932), wife of Lafcadio Hearn Setsuko Matsunaga Nishi (1921–2012), Japanese pioneering community activist and researcher , Japanese yōga painter , Japanese volleyball player , Japanese swimmer , Japanese novelist , Japanese–Canadian nuclear disarmament campaigner , Japanese novelist , Japanese volleyball player

Fictional characters Setsuko, a character in the film Grave of the Fireflies Setsuko Ohara, a character in the game Super Robot Wars Z

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