Ruff may refer to:
Places Ruff, Virginia, United States, an unincorporated community Ruff, Washington, United States, an unincorporated community
Fictional characters Ruff Ruffman, the animated dog host of Fetch! With Ruff Ruffman Ruff, a cat on The Ruff & Reddy Show Ruff, a dog in Dennis the Menace Ruff, a boy in 40 Winks Ruff, in the video game Dragon Quest VII Ruffs, a playable character in the video game Brawl Stars
Other uses Ruff (bird) (Calidris pugnax or Philomachus pugnax), a bird in the wader family Ruff (cards), to play a trump card to a trick in cards Ruff (clothing), a very wide collar, usually stiff and thick Ruff (surname) Ranik Ultimate Fighting Federation, a Chinese mixed martial arts organization Real Ulster Freedom Fighters, a loyalist paramilitary organisation in Northern Ireland Australian herring or ruff, a fish , two minesweepers Ruff, a percussion rudiment similar to the drag Ruff, a 2015 album by Born Ruffians
See also Ruff and Honours, a 17th-century card game Ruff-Ruff, Tweet and Dave, an American children's CGI animated television series Ruffe, fish in the genus Gymnocephalus Ruffs (mixtape), by Kenny Mason