Mathiot is a surname. Notable people with this surname include:
Ginette Mathiot (1907–1998), French food writer and home economist John Mathiot (), American politician Joshua Mathiot (1800–1849), American politician Lorenzo Mathiot (born 1977), Seychellois footballer Madeleine Mathiot (1927–2020), American linguist Michel Mathiot (1926–1999), French gymnast Télie Mathiot (born 1987), French pole vaulter Ulric Mathiot (), Seychellois footballer and manager
See also