Di Lorenzo or DiLorenzo is an Italian surname. It derives from the name Lorenzo, the surname indicates those of the family of a Lorenzo. Notable people with the surname include:
Francesca Di Lorenzo (born 1997), Italian-American tennis player Giovanni Di Lorenzo (born 1993), Italian footballer Giovanni di Lorenzo (journalist) (born 1959), Italian-German journalist Rossana Di Lorenzo (1938–2022), Italian actress Tina Di Lorenzo (1872–1930), Italian actress Thomas DiLorenzo (born 1954), Italian-American Professor Rosario DiLorenzo (born 1994), Italian-American Emmy Award Winner Melanie DiLorenzo (born 2002), Italian-American professional drummer