The 1990–91 Wake Forest Demon Deacons men's basketball team represented Wake Forest University as a member of the Atlantic Coast Conference during the 1990–91 NCAA men's basketball season. The team was led by 2nd year head coach Dave Odom, and played their home games at LJVM Coliseum in Winston-Salem, North Carolina.

Wake Forest finished in a tie for third in the ACC regular season standings with an 8–6 conference record. The team lost to Virginia in the quarterfinal round of the ACC tournament. Despite the early exit from the conference tournament, the Demon Deacons received the No. 5 seed in the Southeast region of the NCAA tournament the school's first appearance in seven years. The team defeated No. 12 seed Louisiana Tech before losing to No. 4 seed Alabama in the round of 32. This season formed the foundation of a school-record seven straight NCAA tournament appearances between 1991 and 1997.

Electrifying freshman Rodney Rogers was named ACC Rookie of the Year and head coach Dave Odom was named ACC Coach of Year for the first time.

Previous season Wake Forest finished in last place in the ACC regular season standings and were eliminated in the quarterfinals of the ACC tournament. In Coach Dave Odom's first season, the Demon Deacons had a record of 12–16 (3–11 ACC).

Roster

Schedule and results

!colspan=9 style=| Non-conference regular Season

!colspan=9 style=| ACC Regular Season

!colspan=9 style=| ACC Tournament

!colspan=9 style=| NCAA Tournament

Rankings

Awards and honors Rodney Rogers ACC Rookie of the Year Dave Odom ACC Coach of the Year

References