Hypericum styphelioides is a perennial flowering plant in the St. John's wort family Hypericaceae. It is endemic to Cuba.
Infraspecifics Hypericum styphelioides has three accepted subspecies. Hypericum styphelioides subsp. styphelioides: western Cuba Hypericum styphelioides subsp. moaense: western and central Cuba, Isla de Pinos Hypericum styphelioides subsp. clarense: eastern Cuba
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