The following is a list of prominent Afro-Guyanese, or people of Afro-Guyanese descent.
Notable people of Guyanese descent
Deborah Cox, Canadian R&B singer-songwriter with longest-running #1 R&B track on charts Jason David, Canadian-born American football cornerback JDiggz, Canadian rapper, Afro-Guyanese mother Melanie Fiona, Canadian R&B singer-songwriter, who is also of Indo-Guyanese descent Nubya Garcia, English saxophonist and jazz musician, Guyanese mother David Lammy, British-born politician and lawyer Tessa McWatt, Guyanese-born Canadian writer Des'ree, English singer, Afro-Guyanese mother Sonnet L'Abbé, Canadian writer Yolanda T. Marshall, Guyanese-born Canadian writer Dawnn Lewis, American actress Leona Lewis, singer and the first winner of "The X Factor" (series 3), Guyanese father Jermain Jackman, singer and "The Voice UK" (2015) winner Derek Luke, American actor Maestro, Canadian rapper and actor Nicole Narain, Playboy model, has an Afro-Guyanese mother and her father, who is of mixed Indo-Guyanese and Chinese-Guyanese descent Trevor Phillips, British politician CCH Pounder, Guyanese-born American actress Joy Reid, American news correspondent for MSNBC, Afro-Guyanese mother Rihanna, Barbados-born singer/billionaire, Afro-Guyanese mother Saukrates, Canadian rapper/singer Eon Sinclair, bassist of Canadian rock/ska/reggae band Bedouin Soundclash Sean Patrick Thomas, actor (Save the Last Dance and Barbershop) Phil Lynott, English-born frontman of the Irish rock band Thin Lizzy, Afro-Guyanese father Wretch 32, British rapper, Guyanese mother Vanessa Lee Chester, former American child actress ("A Little Princess", "Harriet the Spy", and "The Lost World: Jurassic Park") Letitia Wright, actress, who is best-known for playing Shuri in the 2018 film version of "Black Panther" and the 2022 sequel "Black Panther: Wakanda Forever" Roy Woods, Canadian R&B artist Saint JHN, Guyanese-American rapper Shaunette Renée Wilson, Guyanese-born American actress ("The Resident", "Billions", and "Black Panther")
Arts
Eddy Grant, musician Ram John Holder, actor and musician Preme, Canadian rapper Red Café, Guyanese-American rapper
Sports
Clifford Anderson, former British Empire featherweight contender Basil Butcher, former Guyanese and West Indian cricketer Colin Croft, former Guyanese and West Indian cricketer Chelsea Edghill, Guyanese table tennis player Roy Fredericks, former Guyanese and West Indian cricketer Lance Gibbs, former Guyanese and West Indian cricketer Vivian Harris, former WBA super lightweight champion Roger Harper, former Guyanese and West Indian cricketer Carl Hooper, former West Indian cricket captain Ezekiel Jackson, professional wrestler Clayton Lambert, American, Guyanese and West Indian cricketer, scored the most runs for Guyana Andrew Lewis, former WBA welterweight champion Clive Lloyd, former Guyanese and West Indian cricketer Aliann Pompey, Guyanese 400 meter sprinter Alana Shipp - Barbadian IFBB professional bodybuilder Mark McKoy, Guyanese-born Canadian sprinter Michael Anthony, Guyanese Boxer
Politicians and social leaders
Forbes Burnham, President of Guyana, 1980-1985 Hubert Nathaniel Critchlow, father of the trade union movement in British Guiana Cuffy, leader of the Berbice slave uprising Karen de Souza (born 1958), women and children's activist Jack Gladstone, leader of the Demerara rebellion of 1823 David A. Granger, President of Guyana Hamilton Green, 1st Muslim Prime Minister of Guyana, and in the Western world, 1985-1992 Desmond Hoyte, President of Guyana, 1985-1992 Sam Hinds, former President of Guyana, Prime Minister of Guyana Eusi Kwayana, former Guyanese cabinet member and veteran politician Lincoln Lewis, trade union leader Quamina, leader of the Demerara rebellion of 1823 Ptolemy Reid, former Prime Minister of Guyana
Academics
John Agard, playwright, poet and children's writer George Granville Monah James, historian and author Egbert Martin, 19th-century Guyanese poet of mixed African and European ancestry Walter Rodney, historian and political activist Ivan Gladstone Van Sertima, associate professor of Africana Studies at Rutgers University
Models Arti Cameron