The 2021 Potchefstroom Open was a professional tennis tournament played on hard courts. It was the second edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Potchefstroom, South Africa between 8 and 14 February 2021.

Singles main-draw entrants

Seeds Country Player Rank1 SeedPrajnesh Gunneswaran1301Benjamin Bonzi1342Marc-Andrea Hüsler1433Jay Clarke1904Brayden Schnur2085Cem İlkel2146Peter Polansky2207Roberto Cid Subervi2228 1 Rankings are as of 1 February 2021.

Other entrants The following players received wildcards into the singles main draw: Robbie Arends Vaughn Hunter Khololwam Montsi

The following players received entry into the singles main draw using protected rankings: Jenson Brooksby Julien Cagnina

The following players received entry from the qualifying draw: Mirza Bašić Liam Broady Nick Chappell Ryan Peniston

Champions

Singles

Benjamin Bonzi def. Liam Broady 7–5, 6–4.

Doubles

Marc-Andrea Hüsler / Zdeněk Kolář def. Peter Polansky / Brayden Schnur 6–4, 2–6, [10–4].

References