Ace in the Hole may refer to:

Music Ace in the Hole (album), an album by Elvin Bishop Ace in the Hole Band, the backup band for George Strait "Ace in the Hole" (Cole Porter song) "Ace in the Hole" (George Strait song) written by Dennis Adkins "Ace in the Hole", a song by Paul Simon on the album One-Trick Pony "Ace in the Hole", a song composed in 1909 by James Dempsey and George Mitchell, and recorded by many artists including Bobby Darin and Johnny Mercer on Two of a Kind

Other uses Ace in the Hole (1942 film), an animated cartoon short subject Ace in the Hole (1951 film), a film starring Kirk Douglas "Ace in the Hole" (short story), a 1955 story by John Updike Ace in the Hole (anthology), edited by George R. R. Martin Ace in the Hole, a 2009 sitcom pilot starring Adam Carolla Having an ace as a hole card in poker That Old Ace in the Hole, a 2002 novel by Annie Proulx