Gayles may refer to:
Places Gayles, North Yorkshire, a village in England Gayles, Virginia, an unincorporated community in King George County, Virginia, United States
People Billy Gayles (born 1931), American rhythm & blues drummer and vocalist Caesar Felton Gayles (born 1900), American football and basketball coach Darrin P. Gayles (born 1966), American judge Fred Gayles (born 1966), American former arena football wide receiver/linebacker in the Arena Football League George W. Gayles (born 1844), African-American Baptist minister and politician holding offices in Mississippi Joseph Gayles (born 1844), American criminal, one of the leaders of the Patsy Conroy Gang in New York City
See also Gayle (disambiguation) Gaylesville, Alabama