Lupe is a given name, short for Guadalupe, and may refer to:

People Lupe Aquino (born 1963), Mexican boxer Lupe Fiasco (born 1982), American hip hop artist Lupe Ontiveros (1942–2012), Mexican-American film and television actress Lupe Pintor (born 1955), Mexican boxer Lupe Sanchez (1961–2025), American football player Lupe Vélez (1908–1944), Mexican-American actress Lupe (Arrested Development), a fictional character from the television series Arrested Development Lupe, a fictional character from the television series Fanboy & Chum Chum

Other uses Lupé, a commune in the Loire department, France Lupe (horse), a racehorse Pacific imperial pigeon, a pigeon found in Polynesia. SAR-Lupe, a German military reconnaissance satellite system

See also Lope (disambiguation) Lopez Guadalupe (disambiguation)