The 2020–21 Southern Miss Golden Eagles basketball team represented the University of Southern Mississippi during the 2020–21 NCAA Division I men's basketball season. The team was led by second-year head coach Jay Ladner, and played their home games at Reed Green Coliseum in Hattiesburg, Mississippi as members of Conference USA.
Roster
Schedule and results
!colspan=12 style=|Non-conference regular season
!colspan=12 style=|CUSA regular season
!colspan=12 style=| Conference USA tournament
See also 2020–21 Southern Miss Lady Eagles basketball team
Notes
References