Poignant is a surname. Notable people with the surname include:
Axel Poignant (1906–1986), Australian photographer Bernard Poignant (born 1945), French politician, Member of the European Parliament Jan Poignant (born 1941), Swedish sports shooter Roslyn Poignant (1927–2019), Australian photographic anthropologist Serge Poignant (born 1947), French politician, member of the National Assembly