DSB may refer to:
Science and technology Dictionary of Scientific Biography, a multivolume reference work edited by Charles Coulston Gillespie Double strand break, a break in both DNA strands, part of DNA repair Double-sideband transmission, in telecommunications Dsb, the warm-summer Mediterranean continental climate in the Köppen climate classification DsbA, a bacterial member of the Dsb (disulfide bond) family of enzymes
Organizations De Surinaamsche Bank, Suriname Defense Science Board, of the United States Democrats for a Strong Bulgaria, a Bulgarian political party Department of Internal Security (:ru:Главное управление собственной безопасности МВД России) or Departamenta sobstvennoi bezopasnosti of the Russian Ministry of Internal Affairs, an anticorruption and internal crime detection agency in Russia Deutsche Schallplatten Berlin, another name of VEB Deutsche Schallplatten Deutsche Schule Bratislava, a German international school in Bratislava, Slovakia Deutscher Schützenbund, the German Shooting and Archery Federation Dispute Settlement Body, of the World Trade Organization DSB (railway company) (Danske Statsbaner), a Danish train operating company DSB Bank (Dirk Scheringa Beheer), Netherlands DSB Stadion, a football stadium in Alkmaar, Netherlands sponsored by DSB Bank DSB International School, a German school in Mumbai, India Dutch Safety Board, a Netherlands investigation agency German International School of Cairo (Deutsche Schule der Borromäerinnen Kairo), Egypt German School Beirut (Deutsche Schule Beirut), Lebanon Norwegian Directorate for Civil Protection (Direktoratet for samfunnssikkerhet og beredskap), a Norwegian government organization
Other Dark square bishop, in chess Department Store Battles, a modification for Battlefield 2, a computer game Domestic Stability Buffer, a capital buffer set by a financial regulator in Canada requiring major domestic banks to keep some loan funds in reserve Don Salvador Benedicto, a municipality in the province of Negros Occidental, Philippines "Don't Stop Believin'", a song by American rock band Journey DSB, the ISO 639-2 or SIL International language code for the Lower Sorbian language - Dolnoserbski