A chain reaction in chemistry or physics is a sequence of reactions where a reactive product or by-product causes additional reactions to take place.

Chain reaction or The Chain reaction may also refer to:

Media Chain Reaction (game show), an American game show Chain Reaction (radio), a BBC Radio 4 chat show "Chain Reaction" (Falcon Crest), a 1987 TV episode "Chain Reaction" (Missing You), a 2025 TV episode "Chain Reaction" (Stargate SG-1), a TV series episode Chain Reaction, a novel by Simone Elkeles Chain Reaction, a 1995 video game in the Magical Drop series

Films Chain Reaction (1996 film), starring Keanu Reeves, Rachel Weisz, Morgan Freeman, and Fred Ward Chain Reaction (2017 film) The Chain Reaction, 1980 Australian film starring Steve Bisley

Music Chain Reaction (band) Chain Reaction (record label) Chain Reaction (music venue), defunct music venue in Anaheim, California Albums Chain Reaction (The Crusaders album), 1975 Chain Reaction (Luba album), 1980 Chain Reaction (John Farnham album), 1990 Chain Reaction (Cuban Link album), 2005 Chain Reaction: Yokohama Concert, Vol. 2, a 1977 concert recording by J. J. Johnson and Nat Adderley released in 2002 Chain Reaction, a 2014 album by Distorted Harmony

Songs "Chain Reaction" (Diana Ross song), 1985 "Chain Reaction" (John Farnham song), 1990 "Chain Reaction", from the album The Best by Girls' Generation "Chain Reaction", from the 1974 album Soon Over Babaluma by Can "Chain Reaction", from the 1983 album Frontiers by Journey "Chain Reaction", from the 1985 album Straight No Filter by Hank Mobley "Chain Reaction", from the 1988 album Reach for the Sky by Ratt

Other uses Chain Reaction (horse), a Canadian racehorse Chain Reaction (sculpture), a 1991 American peace monument created by Paul Conrad Chain Reaction Cycles, a retail website focusing on selling cycling goods

See also Nuclear chain reaction, a physical process Chain Reactions (film), a 2024 documentary film Chain reactions in living organisms Chain of events