Mosel is a surname. It may refer to:

Arlene Mosel (1921–1996), American librarian and children's writer Darrel Mosel, American politician Hans von der Mosel (1898–1969), German noble and Nazi army general Ignaz von Mosel (1772–1844), Austrian noble, court official, composer, musician, and music writer Tad Mosel (1922–2008), American playwright and screenwriter Ulrich Mosel (born 1943), German theoretical physicist and professor Ulrike Mosel (born ?), German linguistics writer and professor

See also Mosel (disambiguation) Vanessa Benelli Mosell (born 1987), Italian pianist and conductor Mostel (surname), a similarly spelled surname