William P. Frye (1830–1911) was a U.S. Senator from Maine from 1881 to 1911. Senator Frye or Frye may also refer to:
Donald C. Fry (born 1955), Maryland State Senate Henry Frye (born 1932), North Carolina State Senate Jack Fry (fl. 2010s), Oklahoma State Senate Joseph Fry Jr. (1781–1860), Pennsylvania State Senate Julie Frye-Mueller (born 1963), South Dakota State Senate