Senator Preston may refer to:
Francis Preston (1765–1835), Virginia State Senate James Patton Preston (1774–1843), Virginia State Senate Jean R. Preston (1935–2013), North Carolina State Senate John S. Preston (1809–1881), South Carolina State Senate Platt A. Preston (1837–1900), Washington State Senate William Ballard Preston (1805–1862), Confederate States Senator from Virginia in 1862 William C. Preston (1794–1860), U.S. Senator from South Carolina from 1833 to 1842