Powless is a surname. Notable people with the surname include:
Delby Powless (born 1980), Mohawk lacrosse player Gaylord Powless (1946–2001), Canadian lacrosse player Neilson Powless (born 1996), American cyclist John Powless (1932–2021), American basketball and tennis coach Johnny Powless (born 1993), Canadian lacrosse player Neal Powless, American lacrosse player Paul Powless (1758–1847), Oneida warrior and chief Purcell Powless (1925–2010), Oneida tribal chairman Ross Powless (1926–2003), Mohawk lacrosse player Shayna Powless (born 1994), American racing cyclist
See also Paulus (disambiguation)