Hentsch is a surname. Notable people with the surname include:
Jürgen Hentsch (1936–2011), German actor Nikolai Hentsch (born 1983), Brazilian alpine skier Richard Hentsch, German military officer and aide to Helmuth von Moltke the Younger at the First Battle of the Marne Thierry Hentsch (1944–2005), Swiss-Canadian philosopher and political scientist