George Khoury or Khouri may refer to:

George Khoury (author) (born 1971), writer and journalist in the field of comic books George Khoury (bishop) (born 1970), Greek bishop George Khoury (molecular biologist) (1943–1987), National Cancer Institute researcher George Khoury (murder victim) (1983–2004), a murdered Israeli Arab Christian George Khoury (record producer) (1909–1998), record producer George Khouri (footballer) (born 1962), footballer from Syria George Khoury (actor), actor in films such as Looking for Danger (1957)

See also George Khoury Association of Baseball Leagues Khouri or Khoury, a Levantine surname