The 2000 Big 12 Conference football season represented the 5th season of Big 12 conference football, taking place during the 2000 NCAA Division I-A football season. The season began with non-conference play on Saturday, August 26, 2000. Conference play began on Saturday, September 30, 2000.

At the conclusion of the regular season, Kansas State won the North Division championship with a 11–3 (6–2) record. Oklahoma finished atop the South Division standings, with a perfect regular season 11–0 (8–0).

In the 2000 Big 12 Championship Game, the Oklahoma Sooners, narrowly beat the Kansas State Wildcats by a score of 27–24 in Kansas City, Missouri. With the win, the Sooners advance to the BCS National Championship Game. Kansas State was placed in the Cotton Bowl Classic. A total of 7 Big 12 teams went to bowl games in 2000.

Oklahoma won the BCS National Championship Game at the 2001 Orange Bowl, defeating Florida State, 13–2, in Miami Gardens.

Head coaches Team Head coach Years at school Baylor Kevin Steele 2nd Colorado Gary Barnett 2nd Iowa State Dan McCarney 6th Kansas Terry Allen 4th Kansas State Bill Snyder 12th Missouri Larry Smith 7th Nebraska Frank Solich 3rd Oklahoma Bob Stoops 2nd Oklahoma State Bob Simmons 6th Texas Mack Brown 3rd Texas A&M R. C. Slocum 12th Texas Tech Mike Leach 1st

Regular season Week 1

Date Bye WeekAugust 26 Baylor Colorado Iowa State KansasMissouriNebraska Oklahoma Oklahoma State Texas Texas A&M

Week 2

Date Bye WeekSeptember 2 Oklahoma State Texas

Week 3

Date Bye WeekSeptember 9 Baylor Kansas Kansas State

Week 4

Date Bye WeekSeptember 16 Nebraska Oklahoma

Week 5

Date Bye WeekSeptember 23 Colorado Iowa State Missouri Texas A&M Texas Tech

Week 6

Week 7

Week 8

Week 9

Date Bye WeekOctober 21 Oklahoma Oklahoma State

Week 10

Week 11

Week 12

Week 13

Date Bye WeekNovember 18 Colorado Nebraska Texas Texas A&M

Week 14

Date Bye WeekNovember 25 Baylor Iowa State Kansas Kansas State Missouri Texas Tech

Championship Game

Bowl Games

Bowl games Legend Big 12 win Big 12 loss

Bowl gameDateSiteTelevisionTime (CST)Big 12 teamOpponentScoreAttendance Galleryfurniture.com Bowl December 27, 2000 Astrodome • Houston, TX ESPN 7:00 PM Texas Tech East Carolina L 27–40 76,835 Insight.com Bowl December 27, 2000 Bank One Ballpark • Phoenix, AZ ESPN 7:30 PM Iowa State Pittsburgh W 37–29 41,813 Holiday Bowl December 29, 2000 Qualcomm Stadium • San Diego, CA ESPN 8:30 PM No. 12 Texas No. 8 Oregon L 30–35 60,028 Alamo Bowl December 30, 2000 Alamodome • San Antonio, TX ESPN 8:00 PM No. 9 Nebraska No. 18 Northwestern W 66–17 60,028 Independence Bowl December 31, 2000 Independence Stadium • Shreveport, LA ESPN 7:00 PM Texas A&M Mississippi State L 41–43 36,974 Cotton Bowl January 1, 2001 Cotton Bowl • Dallas, TX FOX 7:00 PM No. 11 Kansas State No. 21 Tennessee W 35–21 63,465BCS National Championship Orange Bowl January 3, 2001 Pro Player Stadium • Miami Gardens, FL ABC 7:00 PM No. 1 Oklahoma No. 3 Florida State W 13–276,835

Rankings are from AP rankings. All times Central Time Zone. Big 12 teams shown in bold.

References