Sappington may refer to:
Places Sappington, Missouri Joseph Sappington House, house in Missouri William B. Sappington House, house in Missouri Sappington Cemetery State Historic Site, historic site in Missouri
People Courtney Sappington, American politician from Kansas Francis Brown Sappington (died c. 1839), American politician and physician from Maryland John Sappington (1776-1856), American physician John S. Marmaduke (1833-1887), American governor of Missouri John Sappington (Maryland politician) (1847–1905), American physician and politician Marc Sappington (born 1978), American spree killer Margo Sappington (born 1947), American choreographer Richard F. Sappington (1861–1930), American politician from Maryland Thomas Sappington (died 1857), American politician from Maryland
Other Sappington Formation, geologic formation in Montana