Wilson Run is a long 2nd order tributary to Sewickley Creek in Westmoreland County, Pennsylvania.
Course Wilson Run rises about 0.5 miles northwest of Mount Pleasant, Pennsylvania, and then flows northwest to join Sewickley Creek at Paintersville.
Watershed Wilson Run drains of area, receives about 41.8 in/year of precipitation, has a wetness index of 368.30, and is about 51% forested.
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