Senator Bruce may refer to:

Members of the United States Senate Blanche Bruce (1841–1898), U.S. Senator from Mississippi from 1875 to 1881 William Cabell Bruce (1860–1946), U.S. Senator from Maryland from 1923 to 1929

United States state senate members George A. Bruce (1839–1929), Massachusetts State Senate Terry L. Bruce (1944–2026), Illinois State Senate Terry Bruce (politician) (born 1975), Kansas State Senate