Saints Constantine and Helena Church may refer to:
Australia Cathedral of Saints Constantine and Helene
Bulgaria Church of Sts. Constantine and Helena (Plovdiv)
Poland The Orthodox Parish of Saints Constantine and Helen in Zgorzelec
Romania Focșani Military Chapel Livedea Gospod Church
North Macedonia Church of Sts. Constantine and Helena (Skopje)
Russia Sts. Constantine and Helen Church, Novocherkassk
Serbia Church of Saints Emperor Constantine and Empress Helena
Turkey Church of Sts. Constantine and Helen (Edirne)
United States
Sts. Constantine and Helen Greek Orthodox Cathedral Saints Constantine and Helen Greek Orthodox Cathedral of the Pacific (Honolulu) Sts. Constantine and Helen Serbian Orthodox Church Sts. Constantine and Helen Chapel Mosque Maryam (former church)