Rufin is a surname and a male given name. Notable people with this name include:
Given name Rufin Anthony (1940–2016), Pakistani Roman Catholic bishop Rufin Molomadan (born 1967), Central African Republic cyclist Rufin Oba (born 1976), Congolese football player Rufin Sudkovsky (1850–1885), Russian Imperial landscape painter
Surname Guillaume Rufin (born 1990), French tennis player Jean-Christophe Rufin (born 1952), French doctor, diplomat, historian, globetrotter and novelist Zomahoun Idossou Rufin (born 1964), Beninese diplomat in Japan
See also Ruffin (name)