Senator Pendleton may refer to:
Members of the United States Senate Florence Pendleton (1926–2020), shadow U.S. Senator from the District of Columbia from 1991 to 2007 George H. Pendleton (1825–1889), U.S. Senator from Ohio from 1879 to 1885
United States state senate members Charles S. Pendleton (1880–1952), Virginia State Senate Joey Pendleton (born 1946), Kentucky State Senate Nathanael G. Pendleton (1793–1861), Ohio State Senate Peggy Pendleton (born 1946), Maine State Senate