Istiqlol is a city in Sughd Region, northern Tajikistan.
Istiqlol may also refer to other places in Tajikistan: Istiqlol, Devashtich District, in Devashtich District Istiqlol, Jayhun District, in Jayhun District Istiqlol, Spitamen, in Spitamen District Istiqlol, Shahrinav District, in Shahrinav District Istiqlol, Shahriston District, in Shahriston District Sarvati Istiqlol, in Kushoniyon District