Senator Case may refer to:
Members of the United States Senate Clifford P. Case (1904–1982), U.S. Senator from New Jersey from 1955 to 1979 Francis H. Case (1896–1962), U.S. Senator from South Dakota from 1951 to 1962
United States state senate members Cale Case (born 1958), Wyoming State Senate Clarence E. Case (1877–1961), New Jersey State Senate Jerome Case (1819–1891), Wisconsin State Senate John Higley Case (1832–1890), Minnesota State Senate Leon D. Case (1877–1939), Michigan State Senate