Santiago Gómez may refer to:
Santiago Gómez Cou (1903–1984), Uruguayan-Argentine actor Santiago Gómez Cora (born 1978), Argentine rugby player Santiago Gómez (footballer, born 1995), Colombian football forward Santiago Gómez (footballer, born 1996), Argentine football forward Santiago Gómez (footballer, born 1998), Colombian football defender Santiago Gómez (footballer, born 2003), Venezuelan football Centre Back