James McHenry (1753–1816) was an American military surgeon and statesman.
James McHenry may also refer to:
James McHenry (novelist) (1785–1845), American writer, physician, and diplomat James W. McHenry (1864–1931), American mayor James McHenry (lawyer), U.S. Department of Justice official
See also James McHenry Jones (1859–1909), American educator, school administrator, businessperson, and minister