Senator Little may refer to:
Betty Little (born 1940), New York State Senate Brad Little (born 1954), Idaho State Senate Clarence B. Little (1857–1941), North Dakota State Senate Finis H. Little (died 1880), Mississippi State Senate Francis Little (American politician) (1822–1890), Wisconsin State Senate Matt Little (born 1984), Minnesota State Senate Russell M. Little (1809–1891), New York State Senate T. D. Little (born 1942), Alabama State Senate Zeb Little (born 1968), Alabama State Senate
See also Senator Littell (disambiguation)