Syson is a surname. Notable people with the surname include:
Antonia Syson (1973–2018), British-American classical scholar specialising in the study of Virgil's Aeneid Alfred Syson (1880–1952), British fencer who competed in the 1912 Summer Olympics Lucinda Syson, nominee for the 2006 Artios Award for Outstanding Achievement in Casting – Big Budget Feature (Drama) Luke Syson (fl. 1990s–2020s), director of the Fitzwilliam Museum Sidney Syson, winner in the 2019 Warwick District Council election