James Wynne may refer to: James Wynne (rugby league) (born 1976), Australian rugby player for France James Wynne (rower) (born 1937), American Olympian James J. Wynne, American physicist James Wynne (died 1709), soldier and MP for County Leitrim (Parliament of Ireland constituency) James Wynne (died 1748), MP for County Sligo (Parliament of Ireland constituency)
See also James Wynn (disambiguation)