The 2020–21 Coupe de France preliminary rounds, Pays de la Loire was the qualifying competition to decide which teams from the leagues of the Pays de la Loire region of France took part in the main competition from the seventh round.
A total of nine teams qualified from the Pays de la Loire preliminary rounds. In 2019–20, FC Challans and Sablé FC progressed furthest in the main competition, reaching the ninth round before losing to Angoulême-Soyaux Charente (3–1) and Pau (on penalties) respectively.
Schedule A total of 522 teams entered from the region. The draw, made on 22 July 2020, required a preliminary round on 23 August 2020. This round featured 300 clubs from the district divisions, with a small number of District 1 teams exempted to the first round. The first round, which saw the Régional 3 teams enter, took place on 30 August 2020. The second round, featuring the entrance of the Régional 2 teams, took place on 6 September 2020.
The third round draw, in which the Regional 1 and Championnat National 3 teams joined the competition, was made on 10 September 2020. The fourth round draw, which saw the Championnat National 2 teams enter, was made on 23 September 2020. The fifth round draw, which saw the entry of the three Championnat National teams from the region, was made on 7 October 2020. The sixth round draw was made on 21 October 2020.
Preliminary round These matches were played on 22 and 23 August 2020.
+ Preliminary round results: Pays de la Loire Tie no Home team (tier) Score Away team (tier) 1. Aiglons Durtalois (11) 3–3 AS Mézeray (10) 2. FC Sud Ouest Mayennais (10) 0–1 US Soudan (10) 3. US La Chapelle-d'Aligné (11) 2–4 EA Baugeois (10) 4. Pomjeannais JA (9) 1–0 AS Mésanger (10) 5. US Tennie-Saint-Symphorien (10) 0–5 US Pré-en-Pail (9) 6. USJA Saint-Martin-Aviré-Louvaine (10) 1–0 ES Belligné-Chapelle-Maumusson (9) 7. ES Averton (11) 2–5 US Alpes Mancelles (10) 8. FC Ménil (10) 0–1 Saint-Vincent LUSTVI (10) 9. US Villepotaise (12) 0–1 ES Pommerieux (10) 10. AS Brée (11) 0–2 ES Champfleur (10) 11. CF Châtelais-Nyoiseau-Bouillé-Grugé (10) 5–3 US Saint-Aubin-des-Châteaux (10) 12. Abbaretz-Saffré FC (10) 6–0 US Renazé (10) 13. FC Ruillé-Loiron (10) 2–1 ES Rougé (11) 14. ES Val Baugeois (11) 1–1 JS Ludoise (9) 15. AS Clermont-Créans (9) 4–1 ES Morannes (10) 16. US Villaines-Malicorne (10) 6–1 JG Coudray (9) 17. FC Loulaysien (10) 3–1 FC Gétigné-Boussay (10) 18. ES Azé (11) 1–1 SC Sainte-Gemmes-d'Andigné (10) 19. FC Entente du Vignoble (10) 0–1 Etoile du Bocage (9) 20. Hirondelles Soullandaises (11) 3–3 Eclair de Chauvé (11) 21. US Vital Frossay (11) 1–1 AFC Bouin-Bois-de-Céné-Châteauneuf (11) 22. AS Riezaise (12) 1–5 Herbadilla Foot (11) 23. AS Sargéenne (10) 2–3 US Chantenay-Villedieu (10) 24. SC Ballon (12) 0–18 JS Parigné-l'Évêque (10) 25. Dollon Omnisports (10) 3–0 AS Étival (10) 26. GSI Saosnois Courgains (11) 0–2 CO Cormes (9) 27. CO Laigné-Ssint-Gervais (10) 3–0 AS Montmirail-Melleray (10) 28. ARC Tillières (11) 1–3 Saint-Martin Treize Septiers (10) 29. US Les Epesses-Saint-Mars (10) 1–3 ES Vallet (9) 30. FC Villedieu-La Renaudière (12) 1–1 AS Landais (10) 31. Olympique Sal-Tour Vézins Coron (10) 5–1 US Bazoges Beaurepaire (10) 32. Val de Sèvre Football (10) 0–1 FC Fief Gesté (9) 33. Bé-Léger FC (10) 4–1 RS Teiphalien Tiffauges (11) 34. FF Mortagne-sur-Sèvre (10) 0–3 Étoile Mouzillon Foot (10) 35. FC Val de Moine (10) 1–2 RS Ardelay (9) 36. Les Farfadets Saint-Paul-en-Pareds (11) 0–4 Saint-Pierre Mazières (9) 37. SS Bailleul Sport (11) 2–5 US Précigné (10) 38. Sainte-Jamme Sportive (10) 2–4 ES Cherré (10) 39. FC Joué-l'Abbé-La Guierche (11) 0–4 ASPTT Le Mans (9) 40. US Savigné-l'Évêque (10) 1–0 AS Saint-Jean-d'Assé (9) 41. ES Montfort-le-Gesnois (10) 1–3 AS Saint-Pavace (10) 42. US Mesnard-Vendrennes (11) 2–0 Gaubretière-Saint-Martin FC (10) 43. ES Vertou (9) 1–1 AS Bruffière Defontaine (9) 44. Legé FC (10) 1–0 FC Bouaine Rocheservière (9) 45. Saint-Michel SF (10) 2–0 ES La Romagne-Roussay (10) 46. US Suplice André Mormaison (10) 0–1 AS Le-Puy-Saint-Bonnet (9) 47. FC Meilleraie-Montournais-Menomblet (10) 0–0 Saint-Georges Guyonnière FC (9) 48. Coëx Olympique (10) 0–0 FC Garnachois (9) 49. AF Apremont-La Chapelle (11) 0–1 Étoile de Vie Le Fenouiller (9) 50. FC Île de Noirmoutier (10) 3–3 Arche FC (10) 51. USM Beauvoir-sur-Mer (10) 1–1 FC Basse Loire (9) 52. FC Falleron-Froidfond (10) 3–4 Bernerie OCA (11) 53. FC Givrand l'Aiguillon (11) 2–7 ES des Marais (9) 54. EM Sallertaine (11) 0–2 Océane FC (10) 55. AS Saint-Gervais (11) 0–3 Bouguenais Football (9) 56. Saint-Gilles-Saint-Hilaire FC (11) 1–1 FC Logne et Boulogne (10) 57. AS Saint-Maixent-sur-Vie (10) 2–7 ES du Lac (10) 58. Commequiers SF (10) 3–2 AS Sud Loire (10) 59. USC Corné (12) 2–6 ES Daguenière Bohalle (11) 60. AS Mauges (11) 1–1 US Saint-Georges-sur-Loire (11) 61. AS Salle-Aubry-Poitevinière (11) 1–3 AS Ponts-de-Cé (9) 62. ASC Saint-Barthélémy-d'Anjou (11) 2–5 Saint MathMénitRé FC (9) 63. Mon Atout FC Angévin (12) 2–0 Saint-Melaine OS (10) 64. AS Val-d'Erdre-Auxence (10) 2–5 US Combrée-Bel-Air-Noyant (10) 65. AS Valanjou (10) 0–4 AS Avrillé (9) 66. Doutre SC (11) 0–6 AS Écouflant (10) 67. FC Louet-Juignéen (11) 1–1 SC Angevin (10) 68. FC Villevêque-Soucelles (11) 3–2 ÉS Trélazé (10) 69. ES Loire et Louet (11) 1–2 AS Saint-Sylvain-d'Anjou (9) 70. ES Varennes Villebernier (12) 1–7 ASVR Ambillou-Château (11) 71. ES Auverse-Mouliherne-Chavaignes-Lasse (11) 0–3 Union Saint-Leger-Saint-Germain-Champtocé Avenir (10) 72. FC Plessis Grammoire (11) 2–0 ASR Vernantes-Vernoil (10) 73. Club du Haut Layon (11) 0–2 AC Longué (11) 74. ES Le Puy-Vaudelnay (11) 2–1 US Mazé (10) 75. UF Allonnes-Brain-sur-Allonnes (10) 3–3 ES Layon (9) 76. Sainte Christine-Bourgneuf FC (10) 1–1 Herblanetz FC (11) 77. FC Bout' Loire-et-Evre (11) 3–4 FC Oudon-Couffé (10) 78. UFC Erdre et Donneau (10) 5–1 FC Ingrandes-le-Fresne (11) 79. Étoile du Don Moisdon-Meilleraye (11) 2–2 FC Fuilet-Chaussaire (10) 80. FC Castelvarennais (11) 3–0 ES Jovéenne (11) 81. Anjou Baconne FC (11) 2–2 Pin Sulpice Vritz FC (11) 82. Les Touches FC (11) 3–1 FC La Pouëze/Saint-Clement-de-la-Place/Brain (10) 83. Réveil Saint-Géréon (10) 1–1 FC Laurentais Landemontais (9) 84. FC Landivy-Pontmain (10) 0–2 FC Lassay (9) 85. AS Chazé-Vern (11) 0–0 AS Chemazé (10) 86. EB Commer (11) 6–1 FC Montjean (10) 87. US Briollay (11) 0–4 AS Ballée (10) 88. SO Candé-Challain-Loiré (10) 1–5 ES Quelainaise (10) 89. CS Lion d'Angers (10) 1–4 ASPTT Laval (10) 90. AS Martigné-sur-Mayenne (9) 4–0 CS Saint-Pierre-des-Landes (10) 91. AS Châtres-la-Forêt (11) 2–2 Moulay Sports (10) 92. CA Voutréen (10) 2–0 CS Javron-Neuilly (10) 93. US Désertines (11) 0–4 US Chantrigné (10) 94. AS La Dorée (11) 0–11 ASO Montenay (10) 95. AF Chemiré-le-Gaudin (11) 0–7 FC Louplande (10) 96. AS Cérans-Foulletourte (11) 0–4 Internationale du Mans (10) 97. US Breilloise (11) 0–2 US Conlie Domfront (9) 98. Anille Braye Foot (10) 1–2 US La Chapelle-Saint-Rémy (9) 99. Football Champagné Sport (11) 0–4 US Bouloire (9) 100. Degré FC (11) 2–0 FC Saint-Georges-Pruillé (10) 101. FA Laval (10) 0–7 SCL Port-Brillet (9) 102. FC Ambrières (10) 4–4 AS Vaiges (10) 103. US Saint-Germain-le-Fouilloux (10) 1–0 AS Le Bourgneuf-la-Forêt (9) 104. US Cigné (9) 0–3 US Saint-Jean-sur-Mayenne (10) 105. US Parigné-sur-Braye (11) 2–2 AS Parné (11) 106. AS Magnils Chasnais (10) 0–1 FC Talmondais (10) 107. FS Champgenéteux (11) 2–2 USB Juvigné (11) 108. Union Saint-Michel-Triaize-Côte de Lumière (10) 3–1 Sainte-Foy FC (10) 109. ES Longevillaise (10) 0–0 Loups Sportifs Sainte-Flaive-des-Loups (9) 110. USE Dompierroise (9) 1–4 JF Boissière-des-Landes (10) 111. RS Les Clouzeaux (10) 0–3 ES Belleville-sur-Vie (10) 112. ES La Copechagnière (11) 1–4 Hermitage Venansault (10) 113. US Bugallière Orvault (12) 3–5 Saint-Joseph de Porterie Nantes (11) 114. Union Brivet Campbon Chapelle-Launay (9) 2–1 FC Toutes Aides Nantes (10) 115. Sympho Foot Treillières (9) 1–3 Petit-Mars FC (10) 116. JA Besné (12) 0–17 La Saint-André (9) 117. ES Notre-Dame-des-Landes (10) 2–3 AS Marsacais (9) 118. FC Fay Bouvron (10) 4–4 ES Dresny-Plessé (9) 119. FC Mesquerais (11) 1–3 Sainte-Reine-Crossac Football (9) 120. AS Guillaumois (11) 0–4 Savenay-Malville-Prinquiau FC (9) 121. Espérance Saint-Yves Nantes (11) 6–2 RAC Cheminots Nantes (12) 122. Saint-Herblain OC (9) 1–2 Orvault RC (10) 123. Donges FC (9) 4–0 Alerte de Méan (10) 124. Saint-Cyr Foot Herbignac (10) 2–5 Héric FC (9) 125. US Marans-Gené (11) 2–3 Le Cellier Mauves FC (9) 126. US Thouaré (9) 1–0 Métallo Sport Chantenaysien (10) 127. AS Landevieille (11) 0–1 ES Saint-Denis-la-Chevasse (9) 128. JA Nesmy (11) 0–2 US Herminoise (10) 129. US Vouvant Bourneau Cezais (12) 0–7 ES Rives de l'Yon (10) 130. SO Fougeré-Thorigny (12) 1–1 Entente Sud Vendée (10) 131. Étoile du Cens Nantes (13) 2–4 Nantes Sud 98 (10) 132. FC Côte Sauvage (10) 1–2 ES Maritime (9) 133. ES Pineaux (11) 0–7 FC Cantonal Sud Vendée (10) 134. AS Sigournais-Saint Germain (12) 1–0 US Autize Vendée (11) 135. SSJA Saint-Mathurin (11) 0–6 FC Généraudière Roche Sud (9) 136. AS Grandchamp Foot (11) 0–0 SC Nord Atlantique (9) 137. AS Damvitaise (12) 1–2 AS Dom-Tom (10) 138. AS Moutiers-Saint-Avaugourd (11) 0–2 US Bournezeau-Saint-Hilaire (9) 139. FC Saint-Philbert-Réorthe-Jaudonnière (11) 0–1 AS Quatre Vents Fontaines (10) 140. FC Vallée du Graon (10) 1–2 Foot Espoir 85 (10) 141. US Landeronde-Saint-Georges (11) 1–5 Saint-Pierre Sportif Nieul-le-Dolent (10) 142. US Vay (11) 1–1 FC Le Gâvre-La Chevallerais (12) 143. Nozay OS (10) 1–1 JA Saint-Mars-du-Désert (9) 144. FC Atlantique Morbihan (19) 0–4 AS La Madeleine (9) 145. FC Trois Rivières (10) 1–0 Amicale Saint-Lyphard (11) 146. FC Stephanois (10) 0–0 Temple Cordemais FC (11) 147. FC Bourgneuf-en-Retz (11) 1–5 AS Maine (10) 148. Lombron Sports (10) 1–2 US Challes-Grand Lucé (10) 149. Saint-Mars SF Vallons de l'Erdre (11) 0–4 FC Longuenée-en-Anjou (9) 150. AG Champigné-Querré (11) 0–0 US Villiers-Charlemagne (10)
First round These matches were played on 30 August, 2 September and 13 September 2020.