The 2020–21 Coupe de France preliminary rounds, Nouvelle-Aquitaine was the qualifying competition to decide which teams from the leagues of the Nouvelle-Aquitaine region of France took part in the main competition from the seventh round.
A total of eleven teams qualified from the Nouvelle-Aquitaine preliminary rounds. In 2019–20, Pau FC progressed furthest in the main competition, reaching the round of 16 before losing to Paris Saint-Germain 0–2.
Schedule A total of 674 teams entered from the region. The draw required a preliminary round involving 132 clubs on 23 August 2020. The remaining 488 teams from the district divisions, Régional 2 and Régional 3 entered at the first round stage on 30 August 2020. The 35 Régional 1 teams entered at the second round stage on 6 September 2020.
The third round draw, which saw the entry of the Championnat National 3 teams, was made on 15 September 2020. The fourth round draw, which saw the entry of the Championnat National 2 teams, was made on 24 September 2020. The fifth round draw was made on 8 October 2020. The sixth round draw was made on 22 October 2020.
Preliminary round These matches were played on 22 and 23 August 2020.
+ Preliminary round results: Nouvelle Aquitaine Tie no Home team (tier) Score Away team (tier) 1. Football Sud Bastide (10) 1–6 AS Pellegrue (12) 2. Pleumartin-La Roche-Posay FC (12) 3–1 Amicale Coussay-les-Bois (11) 3. AS Civaux (11) 7–0 Entente Nanteuil-Verteuil (12) 4. US Oradour-sur-Glane (11) 2–0 FC Chaillac Saillat (12) 5. ES Montignac 16 (11) 1–0 Entente Foot 16 (11) 6. FC Rouillac (11) 1–0 US Pont l'Abbé d'Arnoult (11) 7. FC Saint-Fraigne (11) 0–2 FC de la Soie (11) 8. AR Cherveux (12) 0–4 AS Augé/Azay-le-Brûlé (11) 9. SEPC Exireuil (11) 3–2 AS Sainte-Néomays Romans (12) 10. AS Saint-Martin-lès-Melle (11) 2–0 AS Exoudun (12) 11. FC Canton de Courçon (11) 1–3 US Champdeniers-Pamplie (11) 12. Croutelle FC (12) 3–0 AS Saint-Eloi (11) 13. ASPTT Bessines (12) 4–1 US Chenay-Chey-Sepvret (11) 14. CS Venise Verte (11) 3–2 US Vivonne (11) 15. US Lambon (12) 0–8 Amicale Saint-Martin (12) 16. SC Bédenac Laruscade (12) 4–2 AS Montguyon (11) 17. FC Valence-en-Pitou/Couhé (13) 3–0 ES Aunac (13) 18. AS Saint-Saviol (12) 1–2 US Abzac (11) 19. AS Blanzay (13) 1–0 Espérance Saint-Bonnet-de-Bellac (11) 20. CAS Bouresse (13) 0–3 AS La Jonchère-Saint-Maurice (11) 21. JS Angoulins (11) 1–11 Avenir Autize (11) 22. US Prahecq (12) 2–3 ASS Portugais La Rochelle (11) 23. Entente Voulmentin-Saint-Aubin-du-Plain-La Coudre (11) 2–0 US La Chapelle-Viviers (12) 24. SC Vouzailles (13) 0–2 US Vouillé (11) 25. AS Saint-Christophe 86 (12) 1–3 Bel-Air Rocs OC Poitiers (11) 26. ASA Couronneries (11) 1–1 AS Saint-Léger Montbrillais (11) 27. ASC Portugais Parthenay et de Gâtine (11) 2–4 US Brion 79 (11) 28. ASC Poitiers-Biard (11) 2–1 ES Saint-Amand-sur-Sèvre (11) 29. SC L'Absie-Largeasse/Moutiers-sous-Chantmerle (11) 3–0 CDJ Pompaire (12) 30. US Vergentonnaise (12) 2–1 FC Jardres (12) 31. ES Vouneuil-sous-Biard (12) 4–1 AS Coulonges-Thouarsais (11) 32. FC ASM (11) 2–3 US Leigné-sur-Usseau (11) 33. ES Boismé Clessé (12) 1–1 FC Chiché (11) 34. AS Colombiers (13) 4–2 US Mirebeau (11) 35. FC Saint-Jean-Missé (11) 5–1 US Cissé (12) 36. SC Champagné-Saint-Hilaire (12) 0–3 Diables Bleus Bersac (11) 37. US Availles-Limouzine (14) 1–8 Fontafie FC (11) 38. CS Chatain (12) 1–0 Entente Saint-Maurice-Gençay (14) 39. CMS Haut-Médoc (11) 2–3 Alerte Cussacaise FC (11) 40. Saint-Aulaye Sports (11) 1–7 AS Pugnac (10) 41. JS Grand Champagne (11) 1–3 US Coutras (11) 42. AS Sauveterrienne (11) 2–0 AS Beautiran FC (12) 43. AS Morizes (11) 0–6 ES Mazères-Roaillan (11) 44. Union Saint-Jean (11) 0–1 SC Monségur (11) 45. US Allemans-du-Dropt (11) 1–1 SC Saint-Morillon (11) 46. US Farguais (11) 1–3 SJ Yvrac (11) 47. SC Astaffortais (11) 1–1 SJ Bergerac (11) 48. RC Dax (11) 1–1 SC Taron Sévignacq (11) 49. Arranoak FC (11) 1–2 Kanboko Izarra (11) 50. Monein FC (11) 0–1 Entente Haut Béarn (11) 51. FC Cubzac-les-Ponts (11) 4–0 AS Saint-Germain-Chantérac (11) 52. AS Coursac (11) 2–6 APIS en Aquitaine (12) 53. FC Pineuilh (11) 1–2 US Ludon (11) 54. Stade Boisseuillais (12) 2–4 US Anais (11) 55. Espoir Haut Vals de Saintonge (11) 2–3 ES Fléac (11) 56. AC Gond-Pontouvre (12) 0–0 CS Trizay-Beurlay (11) 57. FC Spartak Carsac (12) 2–1 AS Villac (12) 58. CA Brignac (11) 2–4 FC Pays Arédien (11) 59. AS Portugaise Sarlat (11) 2–1 APCS Mahorais Brive (11) 60. SC Séreilhac (11) 0–1 USA Terrasson (11) 61. FC Coly (12) 8–1 AS Glandon (13) 62. AS Marcillac Clergoux (11) 3–2 FC Saint-Jal (11) 63. Parempuyre FC (11) 3–1 AS Salles-d'Angles (11) 64. Saint-Seurin JC (12) 1–2 AS Avensan-Moulis-Listrac (11) 65. AG Vendays-Montalivet (11) 3–1 JS Abzac (11) 66. Ciboure FC (11) 4–1 Union Saint-Maurice/Grenade (11)
First round These matches were played on 29 and 30 August 2020, with a number postponed until 2, 5 and 6 September 2020.