Rush Holt Sr. (1905–1955) was a U.S. Senator from West Virginia from 1935 to 1941. Senator Holt may also refer to:
David Holt (politician) (born 1979), Oklahoma State Senate Elmer Holt (1884–1945), Montana State Senate Hines Holt (1805–1865), Georgia State Senate Jim Holt (Arkansas politician) (born 1965), Arkansas State Senate Saxon W. Holt (1871–1940), Virginia State Senate