Schultze is a German surname. Notable people with the surname include:

Bernhard Sigmund Schultze (1827–1919), German gynecologist Charles Schultze (1924–2016), U.S. economist Ernst Schulze (disambiguation) several people including: Ernst Schulze (poet), a German Romantic poet Gottlob Ernst Schulze, a German philosopher Ernst Schulze (chemist), a German Chemist and the grandson of Gottlob Ernst Schulze Sadananda, born Ernst-Georg Schulze, a German Gaudiya Vaishnavist swami Fritz Schultze (1846–1908), German philosopher Gottlob Ernst Schulze (1761–1833), German philosopher, grandfather of biochemist Ernst Schulze Hans-Peter Schultze (born 1937), German-American paleoichthyologist Max Schultze (1825–1874), German microscopic anatomist Norbert Schultze (1911–2002), German composer of film music Rainer Schultze-Kraft (1941–2024), German agronomist specialized in tropical agriculture Sven Schultze (born 1978), German basketball player

See also Schultze Gets the Blues, a 2003 film directed and written by Michael Schorr