Jesse Bledsoe (1776–1836) was a U.S. Senator from Kentucky from 1813 to 1814, and also served in the Kentucky State Senate; Senator Bledsoe may also refer to:
Amanda Mays Bledsoe (born 1978), Kentucky State Senate Anthony Bledsoe (1733–1788), North Carolina State Senate and Tennessee State Senate Cecile Bledsoe (born 1944), Arkansas State Senate William H. Bledsoe (1869–1936), Texas State Senate