Mechanicus may refer to:
Philo of Byzantium (ca. 280 BC – ca. 220 BC), also known as Philo Mechanicus, an ancient Greek engineer and writer Athenaeus Mechanicus, an ancient Greek author of a book on siegecraft, active 1st century BC Warhammer 40,000: Mechanicus, a 2018 video game
See also Mechanic (disambiguation) Mechanicus Kretz' House, a historic building in Copenhagen, Denmark