Melvoin is a surname. Notable people with the surname include:
Jeff Melvoin, American television writer, producer, and educator Jonathan Melvoin (1961–1996), American musician Mike Melvoin (1937–2012), American jazz pianist, composer, and arranger Susannah Melvoin (born 1964), American singer-songwriter Wendy Melvoin (born 1964), American guitarist and singer-songwriter