Watermeyer is a surname. Notable people with the surname include:
Egidius Benedictus Watermeyer (1824–1867), Cape Colony judge Ernest Frederick Watermeyer (1880–1958), South African chief justice Frederick Stephanus Watermeyer (1828-1864), Cape Colony journalist, advocate, and politician Philip Johannes Andries Watermeyer (1825-1897), Cape Colony politician Stefan Watermeyer (born 1988), South African rugby union player