Germishuys is a surname. Notable people with the surname include:
Gerrie Germishuys (born 1949), South African rugby union player Hanco Germishuys (born 1996), South African born American rugby union player Ross Geldenhuys (born 1983), South African rugby union player Deon Germishuys (born 1999), South African professional golfer Gerrie Germishuys (born 1949), South African rugby union player Louis-Marc Germishuys (born 1967), South African cricketer