Nyhus is a surname. Notable people with the surname include:
Ani Nyhus (born 1983), Canadian softball pitcher Åshild Breie Nyhus (born 1975), Norwegian musician Egil Nyhus (born 1962), Norwegian illustrator Ingfrid Breie Nyhus (born 1978), Norwegian pianist Svein Nyhus (born 1962), Norwegian illustrator and writer of children's books Sven Nyhus (born 1932), Norwegian folk musician, fiddler, composer and musicologist