National Secondary Route 222, or just Route 222 (, or ) is a National Road Route of Costa Rica, located in the San José, Cartago provinces.
Description In San José province the route covers Desamparados canton (Frailes, San Cristóbal, and Rosario districts) and Aserrí canton (Tarbaca and San Gabriel districts).
In Cartago province the route covers Cartago canton (Corralillo district) and El Guarco canton (San Isidro district).
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